USA 87 , 71857189 (1990)
This activation enhances insulin sensitivity, allowing cells to utilize glucose more efficiently and lowering blood sugar levels
Kehoe, P.G., The coming of age of the angiotensin hypothesis in Alzheimers disease: progress toward disease prevention and treatment
Indeed, c-myc induces the transcription of glutamine transporters, such as SLC1A5/ASCT2, and also promotes the expression of glutamine-catabolized enzymes such as glutaminase 1 (GLS1) and carbamoyl-phosphate synthetase 2 - aspartate transcarbamylase - dihydroorotase (CAD), in order to encourage glutamine uptake by converting glutamine to glutamate [19-21]
The mechanism involves the interaction of SAM with SAMTOR, an S-adenosylmethionine sensor that regulates the mTORC1 pathway (Gu et al., 2017)
It is not legally available for individual prescription at standard or compounding pharmacies